Real World Evidence for HEOR Professionals

In order to drive the best healthcare decision making and improve health outcomes, HEOR leaders are looking at ways to augment their methodologies to improve clinical specificity. Real-world evidence (RWE) helps teams better understand what factors lead to treatment selection (and/or change), and how to understand whether patients are benefiting from their prescribed therapies.

While methods exist today that use RWD to understand when physicians are prescribing your brand and which types of patients are receiving it, this data has limitations. Typical sources used for this type of analysis include anonymized prescription and medical claims data. This provides information on what is occurring, but only limited insights into why. By gaining consistent access to updated clinical diagnostics results, your HEOR team is better able to understand the reasons for, or outcomes of, targeted treatment decisions.

Patient Journey Mapping

While every patient journey is different, there are commonalities, or profiles, which  can provide additional insights to improve education in the market about your brand, and ultimately, to improve ROI.

The ability to better understand clinical diagnostic testing patterns and usage is a key component in understanding the patient journey, the clinical timeline between diagnosis and treatment, and the factors that inform specific drug-therapy selection for patients.

Uncovering new insights by exploring lab-testing result data will benefit you with a more detailed understanding of disease patterns.

The use of diagnostic laboratory-testing data linked with other anonymized real-world data (RWD) can yield meaningful insights on why treatment decisions are made, and a better understanding of opportunities for your medication to be successfully prescribed and monitored.

In gaining consistent access to updated clinical diagnostics results, your company is better able to understand the reasons for, or outcomes of, treatment decisions.

You’ll receive better results on:

  • Targeted patient journeys
  • Market size assessments
  • Therapy outcome measurement
  • New opportunity identification
  • Better testing hypotheses

Laboratory testing is used frequently in many markets to (1) Confirm a suspected diagnosis (2) Determine what therapy is most appropriate (3) Monitor disease control or progression (4) Ensure that current therapy is being tolerated by the patient.  Other sources of Real World Data – like medical claims – may identify that a lab test was ordered but the results aren’t available. The results are key as they will influence a physician’s decision making for the patient.

An ongoing alert that is based on the timing of lab-testing records — with clinical results — gives stakeholders  a better understanding of the patient’s healthcare  journey, and the ‘why‘ in the analysis when patients change therapies or undergo additional testing or procedures. The lab results may also indicate an outcome the researcher is looking to identify —  such as  disease progression or relapse, or a side effect of a therapy.

Lab Result Outcomes

Once your product is approved for use, detailed information on how to prescribe and oversee its appropriate use is provided in the prescribing instructions. In some cases, this includes the routine monitoring of certain health indicators, such as liver and kidney function. Specific directives may be given regarding dosing adjustments or discontinuation of the product based on patients’ clinical lab-testing results associated with these key indicators. When clinical lab-testing is conducted and results are received by the physician, they can then make an informed decision about adjusting dose or therapy based on the results of those tests.

Prognos solutions identify where in the patient journey a guideline may not have been followed, or where there was an outlier test result.

Understanding the correlation of lab results with other data sets in the patient journey will enhance informing whether physicians might need additional education to ensure that prescribing instructions are followed consistently. Armed with this knowledge, you and the healthcare provider can change patient outcomes.

Data Linkage Partners

Prognos works with industry leading claims data partners to enhance insights for our clients. Our partnership with Datavant expands your ability to integrate our standardized, enriched lab data sets with other and emerging data partners and health ecosystems.